Combined macro / mesoporous microelectrode arrays 1 ( MEAs ) for low noise extracellular recording of neural

Combined macro/mesoporous microelectrode arrays 1 (MEAs) for low noise extracellular recording of neural 2 networks 3 4 5 6 Matthias Heim, Lionel Rousseau, Stéphane Reculusa, Veronika Urbanova, 7 Claire Mazzocco, Sébastien Joucla, Laurent Bouffier, Karel Vytras, Philip 8 Bartlett, Alexander Kuhn, Blaise Yvert 9 10 11 12 13 1. Univ. Bordeaux, ISM, UMR5255, Bordeaux, F-33607 Pessac, France 14 2. CNRS, ISM, UMR5255, Bordeaux, F-33607 Pessac, France 15 3. ESIEE-Paris, ESYCOM, University Paris EST, Cité Descartes BP99, Noisy-Le16 Grand, F-93160 France 17 4. Department of Analytical Chemistry, Faculty of Chemical Technology, University 18 of Pardubice, 53210 Pardubice, Czech Republic 19 5. Univ. Bordeaux, Institut des Neurosciences Cognitives et Intégratives d’Aquitaine, 20 UMR5287, Bordeaux, F-33405 Talence, France 21 6. CNRS, Institut des Neurosciences Cognitives et Intégratives d’Aquitaine, 22 UMR5287, Bordeaux, F-33405 Talence, France 23 7. School of Chemistry, University of Southampton, Highfield, Southampton SO17 24 1BJ, UK 25 26 27 28 29 30 Abbreviated title: Low-noise macro/mesoporous MEAs 31 32 33 34 35 36 37 38 Corresponding author: 39 Blaise Yvert, PhD. 40 CNRS and Université de Bordeaux 41 Institut des Neurosciences Cognitives et Intégratives d’Aquitaine, UMR 5287 42 Bâtiment B2 43 Avenue des facultés 44 33405 Talence cedex 45 Tel. +33 5 40 00 25 73 46 Fax. +33 5 40 00 25 61 47 Email. [email protected] 48 49 Articles in PresS. J Neurophysiol (June 27, 2012). doi:10.1152/jn.00711.2011